Shu-Feng Zhou Selected Research

plumbagin

1/2015	Plumbagin induces G2/M arrest, apoptosis, and autophagy via p38 MAPK- and PI3K/Akt/mTOR-mediated pathways in human tongue squamous cell carcinoma cells.
1/2015	Plumbagin elicits differential proteomic responses mainly involving cell cycle, apoptosis, autophagy, and epithelial-to-mesenchymal transition pathways in human prostate cancer PC-3 and DU145 cells.
1/2015	Induction of apoptosis and autophagy via sirtuin1- and PI3K/Akt/mTOR-mediated pathways by plumbagin in human prostate cancer cells.
1/2015	Plumbagin suppresses epithelial to mesenchymal transition and stemness via inhibiting Nrf2-mediated signaling pathway in human tongue squamous cell carcinoma cells.
1/2015	Plumbagin induces cell cycle arrest and autophagy and suppresses epithelial to mesenchymal transition involving PI3K/Akt/mTOR-mediated pathway in human pancreatic cancer cells.
3/2014	Plumbagin induces apoptotic and autophagic cell death through inhibition of the PI3K/Akt/mTOR pathway in human non-small cell lung cancer cells.
8/2013	Plumbagin induces the apoptosis of human tongue carcinoma cells through the mitochondria-mediated pathway.

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Shu-Feng Zhou Research Topics

Disease

70	Neoplasms (Cancer) 01/2022 - 01/2006
14	Inflammation (Inflammations) 11/2015 - 06/2009
11	Breast Neoplasms (Breast Cancer) 01/2016 - 01/2006
8	Drug-Related Side Effects and Adverse Reactions 05/2019 - 03/2006
8	Hepatocellular Carcinoma (Hepatoma) 01/2018 - 02/2007
6	Carcinoma (Carcinomatosis) 01/2022 - 08/2013
6	Carcinogenesis 11/2016 - 08/2007
6	Fibrosis (Cirrhosis) 11/2015 - 01/2009
6	Alzheimer Disease (Alzheimer's Disease) 11/2015 - 05/2007
6	B-Cell Lymphoma (Lymphoma, B Cell) 01/2015 - 01/2015
5	Neoplasm Metastasis (Metastasis) 01/2022 - 01/2014
5	Leukemia 11/2017 - 01/2014
5	Hypertension (High Blood Pressure) 02/2017 - 05/2008
5	Non-Small-Cell Lung Carcinoma (Carcinoma, Non-Small Cell Lung) 01/2015 - 07/2007
4	Colorectal Neoplasms (Colorectal Cancer) 12/2020 - 03/2006
4	Type 2 Diabetes Mellitus (MODY) 12/2015 - 01/2014
4	Body Weight (Weight, Body) 10/2015 - 05/2006
4	Myocardial Ischemia (Ischemic Heart Diseases) 01/2015 - 03/2009
4	Stomach Neoplasms (Stomach Cancer) 01/2015 - 01/2014
4	Reperfusion Injury 10/2014 - 01/2008
4	Stroke (Strokes) 06/2008 - 05/2007
4	Middle Cerebral Artery Infarction (Middle Cerebral Artery Syndrome) 01/2008 - 05/2007
3	Pancreatitis 11/2017 - 11/2013
3	Abdominal Pain (Pain, Abdominal) 11/2017 - 11/2013
3	Multiple Organ Failure (MODS) 11/2017 - 11/2013
3	Squamous Cell Carcinoma (Epidermoid Carcinoma) 01/2017 - 01/2015
3	Infections 05/2015 - 10/2006
3	Pancreatic Neoplasms (Pancreatic Cancer) 01/2015 - 08/2008
3	Hematologic Neoplasms (Hematological Malignancy) 01/2015 - 01/2015
3	Coronary Disease (Coronary Heart Disease) 06/2008 - 05/2007
3	Central Nervous System Diseases (CNS Diseases) 09/2007 - 04/2007
3	Diarrhea 10/2006 - 05/2006
2	Lung Neoplasms (Lung Cancer) 07/2020 - 08/2014
2	Cardiovascular Diseases (Cardiovascular Disease) 07/2019 - 07/2008
2	Lymphoma (Lymphomas) 11/2016 - 01/2015

Drug/Important Bio-Agent (IBA)

27	Proteins (Proteins, Gene)FDA Link 01/2016 - 01/2006
25	Pharmaceutical PreparationsIBA 11/2017 - 01/2006
11	p38 Mitogen-Activated Protein KinasesIBA 12/2017 - 01/2015
11	Aurora Kinase AIBA 12/2017 - 01/2015
10	MLN 8237IBA 12/2017 - 01/2015
9	EnzymesIBA 01/2022 - 07/2007
8	Biological ProductsIBA 01/2013 - 12/2007
7	Antineoplastic Agents (Antineoplastics)IBA 05/2015 - 12/2007
7	plumbaginIBA 01/2015 - 08/2013
7	CytokinesIBA 01/2015 - 10/2006
7	Irinotecan (Camptosar)FDA LinkGeneric 10/2010 - 05/2006
6	Tumor Necrosis Factor-alpha (Tumor Necrosis Factor)IBA 11/2017 - 10/2006
6	Biomarkers (Surrogate Marker)IBA 01/2015 - 11/2011
5	Folic Acid (Vitamin M)FDA LinkGeneric 01/2021 - 03/2009
5	danusertibIBA 01/2018 - 01/2015
5	Interleukin-6 (Interleukin 6)IBA 11/2017 - 10/2006
5	Member 1 Subfamily B ATP Binding Cassette TransporterIBA 01/2016 - 01/2006
5	tanshinoneIBA 01/2015 - 05/2007
4	SurvivinIBA 12/2020 - 01/2015
4	Aurora KinasesIBA 01/2018 - 01/2015
4	Small Interfering RNA (siRNA)IBA 01/2017 - 01/2012
4	bardoxolone methylIBA 01/2017 - 01/2014
4	Plant ExtractsIBA 11/2015 - 08/2007
3	Glutathione (Reduced Glutathione)IBA 01/2021 - 01/2013
3	Cisplatin (Platino)FDA LinkGeneric 07/2020 - 01/2014
3	InterleukinsIBA 11/2017 - 01/2012
3	EndotoxinsIBA 11/2017 - 08/2009
3	Epithelial Cell Adhesion MoleculeIBA 01/2017 - 01/2015
3	Interleukin-10 (Interleukin 10)IBA 05/2016 - 11/2013
3	Multidrug Resistance-Associated ProteinsIBA 01/2016 - 02/2008
3	MicroRNAs (MicroRNA)IBA 01/2016 - 03/2009
3	Therapeutic UsesIBA 12/2015 - 01/2015
3	Telomerase (Telomerase Reverse Transcriptase)IBA 11/2015 - 07/2007
3	Reactive Oxygen Species (Oxygen Radicals)IBA 05/2015 - 01/2013
3	Proto-Oncogene Proteins c-akt (Protein Kinase B)IBA 01/2015 - 01/2015
3	TriterpenesIBA 01/2015 - 05/2007
3	Cytochrome P-450 CYP2D6 (CYP2D6)IBA 01/2015 - 01/2009
3	Doxorubicin (Adriamycin)FDA LinkGeneric 01/2015 - 12/2013
3	Messenger RNA (mRNA)IBA 01/2015 - 05/2007
3	NADPH Oxidases (NAD(P)H oxidase)IBA 01/2015 - 09/2011
3	TOR Serine-Threonine KinasesIBA 01/2015 - 01/2015
3	CyclodextrinsIBA 01/2015 - 01/2013
3	AntibodiesIBA 01/2015 - 03/2006
3	Beclin-1IBA 01/2015 - 06/2013
3	ChemokinesIBA 01/2012 - 05/2008
3	Ethanol (Ethyl Alcohol)IBA 01/2010 - 03/2009
3	glabridinIBA 01/2008 - 04/2007
2	Hydrogen Peroxide (Hydroperoxide)FDA LinkGeneric 01/2022 - 10/2014
2	CatalaseIBA 01/2022 - 07/2019
2	Paclitaxel (Taxol)FDA LinkGeneric 01/2022 - 01/2015
2	Glucose (Dextrose)FDA LinkGeneric 01/2022 - 03/2009
2	Metal-Organic FrameworksIBA 01/2022 - 01/2021
2	Fluorouracil (Carac)FDA LinkGeneric 12/2020 - 01/2017
2	ImmunosorbentsIBA 07/2019 - 01/2011
2	Cardiac GlycosidesIBA 11/2017 - 05/2015
2	Digoxin (Digitek)FDA LinkGeneric 11/2017 - 05/2015
2	Interleukin-8 (Interleukin 8)IBA 11/2017 - 05/2016
2	Angiotensin IIIBA 02/2017 - 11/2015
2	Prorenin ReceptorIBA 02/2017 - 11/2015
2	Oxaliplatin (Eloxatin)FDA LinkGeneric 01/2017 - 10/2006
2	Somatostatin (Somatotropin Release-Inhibiting Factor)IBA 05/2016 - 11/2013
2	Amylases FDA Link 05/2016 - 11/2013

Therapy/Procedure

33	Therapeutics 01/2022 - 01/2006
16	Drug Therapy (Chemotherapy) 01/2022 - 10/2006
3	Precision Medicine 10/2019 - 12/2013